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Science-based aquaculture has driven the growth of the industry globally.


Many of our clients are able to control vibrio loads in their systems

Members of the Vibrio genus are ubiquitous in marine and freshwater ecosystems.   They are quite varied in their roles although with the vast majority of strains are not pathogenic.  Perhaps the most important role of the vibrios is in the recycling of chitin.  


In fish and shrimp, most of the strains that can cause acute disease are opportunistic. Opportunistic pathogens are only able to produce disease in  weakened and stressed hosts. Obligate pathogens produce disease merely by being present and readily infect healthy and strong hosts.  More than 400 distinct species have been identified and characterized (  There are many  likely thousands of variants (known as strains) of these distinct species. Most are also not pathogens. 

Controlling vibrio loads in the environment is a daunting task.    As an intricate part of stable ecosystems, they belong there and attempts to eradicate them as a whole, while desirable in many instances has the potential for allowing other bacteria to proliferate that can also infect animals opportunistically.    Management of the microbiome is still in its infancy and claims to the contrary are simply not true.  

The Bacillus species in our products compete against vibrio species (and other heterotrophic bacteria) for nutrients. Selected strains of Bacillus  produce  high levels of enzymes that allow  them to degrade a variety of substrates including, critically, the accumulating organic matter that vibrios thrive on.  Incidentally this  is the mechanism by which blue green algae (actually photosynthetic bacteria) are inhibited as well.   


Numerous field results on farms and hatcheries have proven that PRO4000X has potent impacts on the overall vibrio loads and blue green algal growth.

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